3-[(2R)-amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[2-fluoro-6-(trifluoromethyl)benzyl]-6-methyl-2,4(1H,3H)-pyrimidinedione trifluoroacetate - Names and Identifiers
Name | 3-[(2R)-2-Amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione
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Synonyms | Elagolix-002 Desbutyrate Elagolix elagolix intermediate 7 3-[(2R)-2-Amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione 2,4(1H,3H)-Pyrimidinedione, 3-[(2R)-2-amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl- 3-[(2R)-amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[2-fluoro-6-(trifluoromethyl)benzyl]-6-methyl-2,4(1H,3H)-pyrimidinedione trifluoroacetate 3-[(2R)-2-Amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione phosphate salt
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CAS | 830346-50-4
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3-[(2R)-amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[2-fluoro-6-(trifluoromethyl)benzyl]-6-methyl-2,4(1H,3H)-pyrimidinedione trifluoroacetate - Physico-chemical Properties
Molecular Formula | C28H24F5N3O3
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Molar Mass | 545.500476 |
Density | 1.357±0.06 g/cm3(Predicted) |
Boling Point | 625.7±65.0 °C(Predicted) |
Solubility | Dichloromethane; Ethyl Acetate; Methanol |
pKa | 8.49±0.10(Predicted) |
Storage Condition | -20°C Freezer |
3-[(2R)-amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[2-fluoro-6-(trifluoromethyl)benzyl]-6-methyl-2,4(1H,3H)-pyrimidinedione trifluoroacetate - Introduction
3-[(2R)-2-Amino-2-phenylethyl]-5-(2-fluoro-3-methyphenyl)-1-[[2-fluoro-6-(trifluorometyl) phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione, also known as 3-[(R)-2-amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[[2-Fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-piperazinedione, it is often referred to simply as APPI. The following is a description of the nature, use, formulation and safety information of APPI:
Nature:
APPI is an organic compound with the chemical formula C26H20F4N2O3. It is a solid with the appearance of a white crystalline powder. APPI has a high melting and boiling point and is soluble in some organic solvents such as dichloromethane and dimethylformamide.
Use:
APPI is a potential drug molecule with anti-tumor activity. It can be used as an intermediate or raw material for anticancer drugs. In addition, APPI can also be used to study and synthesize biologically active molecules.
Method:
APPI is usually prepared by chemical synthesis. A common preparation method is to use 2-amino -1-phenyl ethanol as the starting material, and carry out a multi-step reaction under appropriate conditions through a chemical reaction, and finally obtain APPI.
Safety Information:
The safety of APPI has not been fully studied, so attention should be paid to its reasonable use and storage. Because APPI is a chemical substance, it may have certain toxicity to human body. When using and handling APPI, it is necessary to take necessary safety measures, such as wearing appropriate protective equipment (such as gloves, protective glasses and protective clothing), and avoid direct contact with skin and eyes. In addition, APPI should be stored in a dry, well-ventilated place, and away from fire and flammable materials.
Please note that this is only a basic introduction to APPI. The specific nature, use, method and safety information need to be further studied and understood according to the actual situation.
Last Update:2024-04-09 21:04:16